Uniklinikum Tübingen

Auditory steady-state responses in fetuses and newborns. A study using fetal Magnetoencephalography (fMEG)

The development of the fetal brain is reflected by the changes in behavioral patterns observed during gestation. However the knowledge about the neurophysiological correlates is limited. Fetal magnetoencephalography (fMEG) is a completely passive and non-invasive method for the recording of fetal brain activity with a temporal resolution in milliseconds. Preliminary studies of our group about fetal auditory brain responses (Draganova R et al., 2005; Draganova R et al., 2007) were carried out at the University of Arkansas for Medical Sciences in Little Rock, Arkansas, USA. In the new project we would like to extent our paradigms and examine if fMEG will be an appropriate method for the recording of Auditory Steady-State responses (ASSR) with brainstem and cortical origin. Until now, the brainstem responses were used as a tool for evaluation of hearing thresholds in adults, children, infants, newborns in term and premature newborns. There were no other studies investigating fetuses for generation of auditory steady-state (ASSR) and auditory brainstem (ABR) responses.

 

 

Principle invesitgator

Rossitza Draganova, PhD

 

Collaboration partner: Department of Obstetrics and Gynaecology, University Hospital Tübingen